Cleaved Lamin A

Depolymerization of the nuclear lamins leads to disintegration of the nuclear envelope. Lamin a c is cleaved by caspase 6 and serves as a marker for caspase 6 activation. The cleavage of lamins results in nuclear dysregulation and cell death 5 6.

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Figure 17 38 The Caspase Cascade Involved In Apoptosis Molecular Molecular Biology Active Site

Figure 17 38 The Caspase Cascade Involved In Apoptosis Molecular Molecular Biology Active Site

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